Huntington's disease is a fatal brain disorder caused by inherited changes in a single gene. These changes lead to destruction of nerve cells in certain brain regions.
Scientists identified the gene in 1993. Anyone with a parent with Huntington's has a 50 percent chance of inheriting the gene, and everyone who inherits it will eventually develop the disorder. In about 1 to 3 percent of cases, no history of the disease can be found in other family members.
Symptoms
Involuntary movements such as twitches and muscle spasms.
Problems with balance and coordination.
Personality changes such as irritability, depression and mood swings.
Trouble with memory, concentration, or making decisions.
The age when symptoms develop and the rate of progression varies from person to person.
There is currently no treatment for Huntington’s. Research is accelerating since scientists identified the gene involved.
More information
Medline Plus: Huntington's www.nlm.nih.gov/medlineplus
Medline Plus is a consumer health information service of the U.S. National Library of Medicine and National Institutes of Health (NIH). This gateway page from Medline Plus Health Topics links to resources from NIH agencies, major medical centers and other sources selected by Medline staff.
Huntington's Disease Society of America
www.hdsa.org
A health organization offering consumer information about Huntington's, funding research, and advocating and promoting awareness among legislators and health professionals.
